Amazon is the “go-to” place for a lot of us, so I wanted to make it easy for you to find the top-rated treatment options available on 

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Antihistamines are typically the doctor’s first choice when treating hives. Here are the top-rated antihistamines on Amazon.

Boiron Histaminum Hydrochloricum

Yes, this sounds like a Harry Potter spell, but it has some amazing ratings! Some folks say they would give this allergy relief 6 stars if they could.

  • Non-Drowsy
  • No Known Side-Effects
  • No Known Drug Interactions
  • Quick-Dissolving Pellets (place under the tongue)

Zyrtec 24 Hour Allergy Relief

This is what I am currently taking and it is a must-have for me, my allergies, and hives.

  • Bundle Pack
  • 24 Hour Relief
  • Prescription Strength

Genexa Homeopathic Allergy Tablets

  • Non-Drowsy
  • No Known Drug Interactions
  • No Artificial Ingredients
  • Vegan
  • Organic

Top-Rated Anti-Itch Creams

These are the top-rated anti-itch creams that are sold on Amazon. These creams all provide instant itch relief.

Benadryl Anti-Itch Gel

  • Topical Itch Relief
  • Cooling Formula
  • Histamine Blocker (anti-histamine)
  • Very Affordable

Caladryl Pink Calamine Itch Relief

  • Instant Itch Relief
  • Great for poison ivy, oak, and sumac
  • Skin Protectant
  • Very Affordable

Caladryl Pink Calamine Skin Protectant Plus Itch Relief, 6 Ounce Bottle (Health and Beauty)

  • Topical analgesic and skin protectant lotion that provided drying action and itch relief
  • Dries the oozing and weeping of poison ivy, poison oak and poison sumac
  • Temporarily relieves pain and itching associated with rashes due to poison ivy, poison oak, or poison sumac
New From: $5.47 ($0.91 / Fl Oz) In Stock

Aveeno Hydrocortisone Anti-Itch Cream

  • 1% Hydrocortisone
  • Anti-Itch
  • Enriched with aloe, Vitamine E, and Oats
  • Multiple Uses

Top Rated Hive Relief Lotions

Amazon has a huge variety of lotions, so I have compiled a few of the top-rated lotions that can assist with relieving your hives.

Pipette Fragrance-Free Lotion

  • Hypoallergenic
  • Safe for Babies
  • 100% Plant-Derived
  • Fragrance-Free
  • Locks in Moisture
  • EWG (Environmental Working Group) Verified

ATTITUDE Moisturizing Body Lotion

  • Hypoallergenic
  • Skin Protectant
  • Free from BHA, BHT, Parabens, and more
  • Fragrance-Free
  • Vegan
  • Biodegradable
  • EWG Verified

CeraVe Itch Relief Lotion

  • Fragrance-Free
  • Contains 3 Essential Ceramides
  • Clinically Tested Itch Relief
  • Fast Acting
  • Lasts up to 8 hours
  • Accepted by the National Eczema Association


Check out, these hive articles to learn more: 

26 Pictures of Hives (Urticaria) on Skin

11 Top Causes for Hives on Skin